Article Database

Explore the transformative power of exercise beyond physical fitness. Discover how regular physical activity enhances mood, reduces stress, improves sleep, boosts self-esteem, sharpens cognitive function, reduces anxiety, fosters social connections, and contributes to emotional well-being.

Oct 19, 2015 • By Yogesh Giri •

Branched Chain Amino Acid Supplements are considered as one of the best way for improving the bodybuilding in the fitness community. Branched Chain Amino Acid Supplement support more health benefits comparing to the other supplements available in market. BCAA supplementation is especially used for maintaining the gain mass and maintaining the muscles with the calorie diet. Many bodybuilding competitors uses the supplement for increasing their body muscles with the maximum strength. Although dieting is one of the option for making the body looking awesome but it will not increase the muscle strength with added mass. Dieting is one of the catabolic function so that it will lead to the muscle breakdown so it is better to choose the BCAA supplementary function. Choosing the Branched Chain Amino Acid Supplements or BCAA will be efficient for increasing the better muscle strength than doing the common exercises. Most of the doctors are also recommending this bcaa supplements for the bodybuilders to improve their muscle strength.

Functions Of BCAA Supplements:

The BCAA supplements will normally establish the branched chain of amino acids for stimulating the protein synthesis. BCAA increases the normal synthesis of cellular machinery that is responsible to carry out the protein synthesis process. Therefore, the BCAA not only increase the protein synthesis rate but also increases cell capacity with protein synthesis. BCAA supplement reduces the protein breakdown rate so that it will decrease the breakdown pathway of protein components and also involved with many protein breakdown factor. Taking the BCAA supplements will be the excellent choice for decreasing protein breakdown and increasing protein synthesis. The supplements will intake the better muscle gain or maintenance in the natural methods. The BCAA supplements also have many other positive benefits with the reduction of protein breakdown with the improved workout intensity. Each of the BCAAs supplement will compete with amino acid tryptophan in the entry of brain as tryptophan converted for neurotransmitter serotonin. When doing exercise, the serotonin level will rise and increase of fatigue perception with less intense workout.

Effective Fueling Strategy:

The BCAA supplementation improves the molecular level with the decrease of muscle loss. Normally the muscle loss will occur with the increased protein breakdown for liberating the amino acids in muscles for fuel. When there is more energy intake, then it will reduce the protein synthesis so for fueling the muscle strength, the BCAA supplements are quite efficient for increasing the Muscle mass with the rate of protein synthesis. There is no side effects taking this wonderful supplements and it will give you the best benefits for increasing the body muscles with the heavy workout. You will be amazed with the increased type of muscle mass and there is no need to take any other supplement added as all the effect will be in the protein synthesis. When you are lifting heavy load then it gives better idea that adapts the body system gaining the maximum immune system. Taking the exact dosage of the supplement is most necessary so that it adds increased muscle.

Apr 10, 2012 • By Uriah •

L-Lysine hydrochloride(C6H15ClN2O2) is an essential free-form amino acid and is one of the 20 most common natural amino acids that the body needs for growth and tissue health. This acid is especially good for helping the body fully absorb calcium as well as reducing thesymptoms of herpes simplex infections. It can also be taken to treat common mouth, sores such as canker sores, and other infections. L-lysine HCl is a molecular form of lysine that is more soluble and easier to digest.

Purity and Concentration
This pharmaceutical-grade amino acid contains no fillers, taste additives or anti-caking agents. This is the hydrochloride form of L-lysine. Hydrochloric acid, a naturally occurring stomach acid, helps break up fats and proteins for quicker digestion in the small intestine and makes the absorption of nutrients through the walls of the intestines easier.

Health Benefits
Like all amino acids, lysine primarily acts and functions as a building block for proteins. It's also a key player in the production of various enzymes, hormones and antibodies and plays a major role in calcium absorption. When works with other essential amino acids, L-lysine HCl can maintain the body's store of nitrogen and is found many sports and bodybuildingsupplements. Bodybuilder, weightlifters and other strength athletes are also using L-lysine in their training regimens because of its role in developing muscle protein.

Lysine is needed to produce carnitine, another amino acid which helps to convert fatty acids into energy. It is also a vital amino acid for growth. The most well-known use for lysine hydrochloride is as an effective treatment for the herpes simplex virus. This virus manifests with painful sores of the mouth, commonly referred to as cold sores. It is believed that lysine helps control these conditions by inhibiting the strength of another amino acid, arginine, which can contribute to the appearance of cold sores. Lysine hydrochloride works to inhibit the production of the herpes simplex virus by slowing, if not eliminating, the effects of the virus.

Food Resources
L-lysine hydrochloride(CAS number 657-27-2 ) helps produce antibodies, assists in proper tissue growth and is needed for synthesizing proteins. Good sources of lysine are foods rich in protein including meat (specifically red meat, pork, and poultry), cheese (particularly parmesan), certain fish (such as cod and sardines), nuts, eggs, brewer's yeast, legumes, soybeans (particularly tofu, isolated soy protein, and defatted soybean flour), spirulina and fenugreek seed.

The soy-based products are particularly beneficial to vegetarians, who may find it hard to get lysine from their diets since vegetables are generally a poor source of lysine, with the exception of legumes (beans, peas, lentils).

Uriah is the freelance writer for e-commerce website in the chemistry. is just a place for you to look for some chemicals! Our guidechem provide the most convenient conditions for the international buyers and let these leads benefit all the business people.

Oct 11, 2009 • By Chris Soares •

BCAA stands for Branch Chained Amino Acids, and it is comprised of Leucine, Valine, and Isoleucine. BCAAs are the main amino acids oxidized during exercise, and due to them totaling 1/3 of the total amino acids in muscle tissue it is important to ingest enough of these during exercise. Additionally, they are the building blocks of muscle, so they are very important to intake. Furthermore, these are essential amino acids which means we need to have them in our diet, but luckily whey protein has a high content of BCAAs.

L-Leucine; is it the most important amino acid?
This amino acid is probably the most important out of the three, as research indicates that during intense exercise is used up quickly compared to the others. One study compared muscle protein turnover after resistance exercise (1). They had three different groups: carbohydrates only, protein and carbohydrates, and finally leucine carbohydrates and protein. Their findings were interesting to say the least as the leucine+carbohydrates+protein group had the largest whole body proteinbalance. Furthermore they explained that it could have been caused from various different pathways such as providing more amino acids for muscle protein synthesis, the leucine increased insulin concentrations when compared to the other groups which could help in protein synthesis (1). They also found that leucine has the ability to help stop protein degradation, which they believe is caused by greater insulin secretion (1). Furthermore, another study found that leucine supplementation stimulates recovery of the skeletal muscle protein synthesis after exercise. However, they used rats in the study but the results are still interesting (2).

BCAA supplementation shown to decrease DOMS and protein degradation!
Another study went over BCAA supplementation on delayed onset muscle soreness (DOMS) and muscle fatigue caused by squats in human. Their results showed that supplementing with BCAAs before squats caused a decrease in DOMS and muscle fatigue (3). Additionally, another study found that exercise causes BCAA degradation, so during resistance training the need for BCAAs goes up (4). Finally they found that supplementing with BCAAs before and after exercise can aid in promoting skeletal muscle synthesis, and also reduce exercise induced muscle damage (4). Overall BCAAs can be a very important supplement and they have a lot of research backing their effectiveness. I think they would work very well during weight loss because it could help decrease DOMS which can limit exercise during caloric deficits. Furthermore they can help stop protein degradation, which too would be good when you are trying to save your precious muscle while losing that fat.

References
1. Gorselink, Marchel, Rene Koopman, Hans Keizer, et al. "Combined ingestion of protein and free leucine with carbohydrate increases postexercise muscle protein synthesis in vivo in male subjects." Journal of Applied Physiology. 288 (2004): E645-653. AJP - Endocrinology and Metabolism. <http://ajpendo.physiology.org/cgi/content/full/288/4/E645#R32>.
2. Anthony, Joshua C., Tracy G. Anthony, and Donald K. Layman. "Leucine Supplementation Enhances Skeletal Muscle Recovery in Rats Following Exercise." Journal of Nutrition 129 (1999): 1102-106. The Journal of Nutrition. <http://jn.nutrition.org/cgi/content/abstract/129/6/1102?ijkey=5ae97f64f5885bebe68276f837286c20ff4670cf&keytype2=tf_ipsecsha>.
3. Mawatari, K., H. Kobayashi, N. Shimomura, et al. "Nutraceutical effects of branched-chain amino acids on skeletal muscle." Journal of Nutrition 136 (2006): 529S-32S. PubMed. <http://www.ncbi.nlm.nih.gov/pubmed/16424141?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_Discovery
Panel.Pubmed_Discovery_RA&linkpos=2&log$=relatedarticles&logdbfrom=pubmed>.
4. Harris, RA., M. Nagasaki, Nakai N., et al. "Exercise promotes BCAA catabolism: effects of BCAA supplementation on skeletal muscle during exercise." Journal of Nutrition 134 (2004): 1583S-587S. PubMed. <http://www.ncbi.nlm.nih.gov/pubmed/15173434?ordinalpos=itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.
Pubmed_Discovery_RA&linkpos=3&log$=relatedreviews&logdbfrom=pubmed>.

Jul 20, 2009 • By Mike Didcky •

There’s so much talk about treating anxiety with medications like Xanax and Valium but often times something as simple as an amino acid supplement can do the trick.  Taurine is an amino acid which plays a major role in the brain as an "inhibitory" neurotransmitter & neuro-modulator and is similiar in structure to the amino acids GABA & L-Glycine, which act to calm or stabilize an excited brain. Taurine acts by regulating the sodium & potassium concentration in the cells & the magnesium level between the cells which all control the electrical activity of the cells & communication between cells.  Thus, taurine also has anti-anxiety & anti-convulsant activity; it has also been found useful in some cases of migraine, insomnia, restlessness, irritability, alcoholism, obsessions, depression, hypomania or mania.

The total ideal body pool of taurine for adults is 12,000- 18,000 mg.  Something to be aware of: since taurine also affects the hypothalamus to help regulate body temperature, higher doses can decrease your temperature & give a senses of chilliness.  Taurine also plays a role in memory & increases the level of a memory neurotransmitter, acetylcholine, in the brain (in animal studies).

Where do you get taurine from?  Taurine is highly concentrated in animal & fish protein or organ meats so strict vegetarians can be at risk for taurine deficiency. Your body can make taurine in the liver and brain from the amino acids, L-Cysteine and L-Methionine and the three enzymes involved in the conversion, all need the pyridoxal-5-phosphate form of Vitamin B6 for this conversion. So make sure you take your vitamins if you have anxiety too!  Also, females tend toward lower taurine levels than males so it is especially important for the ladies to get proper nutrition.  Aim for a proper balance of whole grains, organic vegetables and fruits, nuts and seeds and dairy and poultry a few times a week for balanced nutrition.

Nov 16, 2014 • By Wendy •

the eight B vitamins. It is a water-soluble vitamin relates to the normal functioning of brain and nervous system and the formation of blood. Vitamin B12 is proved to be involved in the metabolism of every cell of the human body, especially affecting DNA synthesis and regulation, and also fatty acid metabolism and amino acid metabolism.

Some evidences show that vitamin B12 may help lower blood level of a substance called homocysteine which is closely related to heart disease and stroke. One analysis of several studies found folic acid cut down homocysteine level by about 1/4 and when folic acid was combined with vitamin B12, homocysteine level was found declined by another 7%, according to an article published in the Journal of the American Medical Association in 2002.

Since homocysteine levels can be lowered with folic acid and vitamin B12 supplements, some scientists start to assume that these vitamins could also work to reduce the risk of memory loss and Alzheimer's disease. But a recent study indicates that taking vitamin B12 and folic acid supplements may not reduce the risk of memory and thinking problems.

This study was published online in the US journal Neurology. Test Subjects of involved in this study are these with high blood levels of homocysteine which is linked to memory loss and Alzheimer's disease. Those 2,919 subjects involved are old people with an average age of 74. They were respectively asked to take a tablet with 400 micrograms of folic acid and 500 micrograms of vitamin B12 or a placebo every day for two years. And their memory and thinking skills were tested at the beginning and end of the study.

The result showed that the homocysteine level of the group of people taking vitamin B12 decreased by more than the group taking the placebo. However, when it came to the thinking and memory ability, there was no big difference between the two groups.

This research has overthrown the results of early studies which shows taking folic acid and vitamin B12 may be beneficial to human's thinking and memory skills. Can Vitamin B12 really reduce the risk of memory loss? This still remains a question needed to be further studied

About homocysteine

Homocysteine is a non-protein α-amino acid. And it is also one of the 20 amino acids in the world, which are molecules that the body requires to synthesize all body proteins. And its reaction occurs usually with the help of vitamin B6, vitamin B12 and folic acid.

This work is contributed by Wendy Kally from Creative Bioarray, a well-recognized biotech company providing the highest standard quality research products and services.